Pluryal Classic comes in a box containing 1 prefilled syringe, 2-27G½” disposable sterile needles, and a package insert. A set of 2 traceability labels is also provided.

What are the benefits of this product?

Help your patients fight the visible signs of aging with Pluryal Classic. This injectable gel is implanted into skin tissue to restore and create volume in the skin for the purposes of aesthetic enhancement. Erase deep wrinkles and folds instantly with results that are noticeable yet natural-looking. 

What is this product made of?

Cross-linked sodium hyaluronate (23mg/ml), phosphate buffer pH 6.7–7.3 q.s., sodium chloride.

How does this work to help my patients?

With age, the skin of our face and body undergoes various physiological and morphological changes, such as a decrease in hyaluronic acid, that may lead to loss of volume in the dermal tissues. This results in undesirable effects on the skin that are especially noticeable on the face, such as wrinkling, loss of elasticity, and sunken areas. Fortunately, filler treatments are available that can help to counteract these effects. Pluryal Classic is made of hyaluronic acid that has been specially modified to increase its stability and improve its performance as an aesthetic enhancer. It is implanted into skin tissue to restore volume thereby smoothing wrinkles and lifting sunken areas, providing the patient with a youthful appearance.

Use Instructions:

How do I use this product?

This dermal filler may only be used by doctors who have received specific training on the injection technique for filling wrinkles. Before the procedure, ensure that your patient is fully informed about the expected result, indications and contraindications, precautions, warnings, and potential side effects of treatment with Pluryal Classic. Inject Pluryal Classic into non-inflamed, healthy skin that has been disinfected. To inject, use the provided 27G½” needle and inject slowly while employing the suitable injection technique. Inject the amount of product necessary to achieve the desired correction. Do not overcorrect. After injecting the product, lightly massage the treated area to ensure even distribution.

How long will the treatment take?

The treatment consists of 1 or 2 sessions, or until the desired level of correction is achieved. The injection sessions usually take 15–30 minutes to complete.

What can I use it for?

Pluryal Classic is indicated for the correction of moderate to severe facial wrinkles and folds, and to add volume to the lips.

What areas should I use this product on?

Pluryal Classic can be used to treat deep wrinkles and folds on the face, particularly glabellar lines, also known as “frown lines,” nasolabial folds, and marionette lines. As well, this product can be injected into the lips for purposes of volumizing and contouring.

How long do the results last?

Results are immediately visible, and generally last from 6–9 months, depending on the individual’s skin type, age, lifestyle, and other factors.

Frequently Asked Questions:

Why should I use this product?

Pluryal Classic is optimized to provide safe and effective treatments with effects that last.

Who is this product intended for?

Individuals who are seeking to correct various age-related facial aesthetic deficiencies such as moderate or severe wrinkles and folds, or to enhance their lips are good candidates to undergo treatment with Pluryal Classic.

There are certain criteria that excludes a potential individual from treatment, including a tendency to develop hypertrophic scars or keloids; have pigment disorders; a history of autoimmune disease or if they are currently receiving immune therapy; known hypersensitivity to hyaluronic acid; if they had received permanent fillers in the area to be treated; if they are pregnant or are breastfeeding; or if they are under 18 years of age.

What are the side effects?

After treatment, patients may experience some reactions related to the injection procedure, which may include redness, itching, tenderness, swelling or bruising at the injection site. These reactions are typically mild and are expected to resolve within 48 hours. Should these symptoms persist or worsen, your patient should seek medical help.

In rare instances, more severe reactions to treatment have been known to occur. These may include, but are not limited to, abscess, bacterial infections, granulomas, foreign body reactions, herpes reactivation, hypersensitivity, filler migration, necrosis from vascular compromise, nodules, and retinal artery occlusion. These effects may have serious consequences and require urgent medical attention. For further information, a full list of contraindications, precautions, and potential adverse events can be found on the package insert.

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